Xiao H, Gong S, Wang J
Union Hospital, Tongji Medical University, Wuhan.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1995;30(1):17-9.
Membranous labyrinth antigen of guinea pigs was prepared. The sera of 33 patients with inner ear disorders of unknown etiology were examined by immunoblotting assay. The autoantibodies against inner ear antigen were found in patient's sera (30.3%). This indicated that the autoimmune activity may play a role in the development of some cases of these diseases. The detection of autoantibodies to inner ear antigen will be of great value to further study on the action of autoimmunological factor contributing to inner ear disorders of unknown etiology.
制备了豚鼠膜迷路抗原。采用免疫印迹法检测了33例病因不明的内耳疾病患者的血清。在患者血清中发现了针对内耳抗原的自身抗体（30.3%）。这表明自身免疫活性可能在这些疾病的某些病例发生中起作用。检测内耳抗原自身抗体对于进一步研究自身免疫因素在病因不明的内耳疾病中的作用具有重要价值。
