Cossa H A, Gloyd S, Vaz R G, Folgosa E, Simbine E, Diniz M, Kreiss J K
Department of Epidemiology, University of Washington, Seattle.
Int J STD AIDS. 1994 Mar-Apr;5(2):117-23. doi: 10.1177/095646249400500208.
A cross-sectional study was conducted among displaced pregnant women in Mozambique to determine the prevalence and correlates of HIV infection and syphilis. Between September 1992 and February 1993, 1728 consecutive antenatal attendees of 14 rural clinics in Zambézia were interviewed, examined, and tested for HIV and syphilis antibodies. The seroprevalence of syphilis and HIV were 12.2% and 2.9%, respectively. Reported sexual abuse was frequent (8.4%) but sex for money was uncommon. A positive MHA-TP result was significantly associated with unmarried status, history of past STD, HIV infection, and current genital ulcers, vaginal discharge, or genital warts. Significant correlates of HIV seropositivity included anal intercourse, history of past STD, and syphilis. In summary, displaced pregnant women had a high prevalence of syphilis but a relatively low HIV seroprevalence suggesting recent introduction of HIV infection in this area or slow spread of the epidemic. A syphilis screening and treatment programme is warranted to prevent perinatal transmission and to reduce the incidence of chancres as a cofactor for HIV transmission.
在莫桑比克的流离失所孕妇中开展了一项横断面研究,以确定艾滋病毒感染和梅毒的患病率及其相关因素。1992年9月至1993年2月期间,对赞比西亚省14个农村诊所连续就诊的1728名产前检查者进行了访谈、检查,并检测了艾滋病毒和梅毒抗体。梅毒和艾滋病毒的血清阳性率分别为12.2%和2.9%。报告的性虐待情况较为常见(8.4%),但以性换钱的情况并不常见。梅毒螺旋体血凝试验(MHA-TP)结果呈阳性与未婚状况、既往性传播疾病史、艾滋病毒感染以及当前的生殖器溃疡、阴道分泌物或尖锐湿疣显著相关。艾滋病毒血清阳性的显著相关因素包括肛交、既往性传播疾病史和梅毒。总之,流离失所孕妇梅毒患病率较高,但艾滋病毒血清阳性率相对较低,这表明该地区最近才出现艾滋病毒感染,或者疫情传播缓慢。有必要开展梅毒筛查和治疗项目,以预防围产期传播,并降低作为艾滋病毒传播辅助因素的硬下疳的发病率。