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[影响重症肌无力胸腺切除术长期疗效的因素]

[Factors influencing long-term results of thymectomy for myasthenia gravis].

作者信息

Jiang Y G

机构信息

Third Affiliated Hospital, Third Military Medical College, Chongqing.

出版信息

Zhonghua Wai Ke Za Zhi. 1993 Dec;31(12):765-7.

PMID:8033712
Abstract

The long-term follow-up results after thymectomy for 92 patients with myasthenia gravis (MG) including 22 patients with thymomatous MG were discussed. All patients were followed up for 3 approximately 73 months (average 23). The surgical effective rate was 88.0% and late mortality 6.5%. Sex and disease duration were not obviously related to prognosis, but the effects were much better in 10 approximately 39 year-old groups than in the other groups. The modified Osserman's clinical classification, acetylcholine receptor (AchR) antibodies and citric acid extract (CAE) antibodies titers in plasma and pathological patterns of the surgical specimens of the thymus are factors affecting long-term results.

摘要

讨论了92例重症肌无力(MG)患者胸腺切除术后的长期随访结果,其中包括22例胸腺瘤型MG患者。所有患者随访约3至73个月(平均23个月)。手术有效率为88.0%,晚期死亡率为6.5%。性别和病程与预后无明显相关性,但10至39岁组的效果明显优于其他组。改良的奥斯勒曼临床分型、血浆中乙酰胆碱受体(AchR)抗体和柠檬酸提取物(CAE)抗体滴度以及胸腺手术标本的病理类型是影响长期结果的因素。

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