Truscott R J, Wood A M, Carver J A, Sheil M M, Stutchbury G M, Zhu J, Kilby G W
Australian Cataract Research Foundation, University of Wollongong, N.S.W.
FEBS Lett. 1994 Jul 11;348(2):173-6. doi: 10.1016/0014-5793(94)00601-6.
A new UV-filter compound, 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside, has been identified in human lenses. The structure suggests that it is derived biosynthetically from tryptophan. Quantification studies on the new compound show that it is the second-most abundant UV-filter compound in the lens with an absorption and fluorescence spectrum similar to that of 3-hydroxykynurenine glucoside.
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