Yaron Y, Botchan A, Amit A, Peyser M R, David M P, Lessing J B
Vitro Fertilization/Embryo Transfer Unit, Serlin Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Fertil Steril. 1994 Aug;62(2):225-32. doi: 10.1016/s0015-0282(16)56868-x.
To review the different aspects of endometrial receptivity as it is reflected in the various modalities of modern assisted reproductive technologies.
The importance of endometrial receptivity and the factors that affect it such as the type of treatment, age, and ovarian function are discussed in this review. Novel approaches to determine receptivity such as Doppler ultrasonography and molecular biology are considered; assisted hatching is also discussed.
Endometrial receptivity cannot, as yet, be directly assessed. Circumstantial evidence suggests that receptivity declines with age, is adversely affected by controlled ovarian hyperstimulation, and is possibly affected by ovarian function. Future studies will have to focus on molecular cell biology and physiology of the endometrium.
回顾子宫内膜容受性在现代辅助生殖技术各种方式中的不同体现。
本综述讨论了子宫内膜容受性的重要性以及影响它的因素，如治疗类型、年龄和卵巢功能。还考虑了确定容受性的新方法，如多普勒超声检查和分子生物学；也讨论了辅助孵化。
目前尚不能直接评估子宫内膜容受性。间接证据表明，容受性随年龄下降，受控制性卵巢过度刺激的不利影响，并且可能受卵巢功能影响。未来的研究将不得不聚焦于子宫内膜的分子细胞生物学和生理学。
