Dennis M, Barnes M A
Hospital for Sick Children, Toronto, Ontario, Canada.
J Dev Behav Pediatr. 1994 Apr;15(2):124-30.
We studied childhood neuropsychologic function in two pairs of low birth weight, same-sex twins reared together but with different patterns of concordance and discordance for intraventricular hemorrhage (IVH) and hydrocephalus (HYD). Same-sex twins have discordant levels of cognitive skills when one twin but not the other develops IVH alone or IVH and HYD at birth. The results bear on several issues: the effects of prematurity, the effects of IVH, the combined effects of IVH and HYD, and the potential applications of the present methodology of pairwise-matched twin comparisons for understanding how different forms of perinatal brain damage affect childhood cognitive functions important for learning.
我们研究了两对低出生体重的同性双胞胎的儿童神经心理功能，这两对双胞胎一起抚养长大，但在脑室内出血（IVH）和脑积水（HYD）方面具有不同的一致和不一致模式。当一对同性双胞胎中的一个在出生时单独发生IVH或同时发生IVH和HYD，而另一个没有时，他们的认知技能水平不一致。这些结果与几个问题相关：早产的影响、IVH的影响、IVH和HYD的联合影响，以及当前配对双胞胎比较方法在理解不同形式的围产期脑损伤如何影响对学习很重要的儿童认知功能方面的潜在应用。
