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与肿瘤以及针对牛桥粒芯蛋白I和II的IgG和IgA抗体相关的罕见棘层松解性大疱性皮肤病。

Unusual acantholytic bullous dermatosis associated with neoplasia and IgG and IgA antibodies against bovine desmocollins I and II.

作者信息

Chorzelski T P, Hashimoto T, Nishikawa T, Ebihara T, Dmochowski M, Ismail M, Jabłońska S

机构信息

Department of Dermatology, Warsaw School of Medicine, Poland.

出版信息

J Am Acad Dermatol. 1994 Aug;31(2 Pt 2):351-5. doi: 10.1016/s0190-9622(94)70171-7.

Abstract

There are unusual cases of pemphigus that have antibodies nonreactive with either pemphigus vulgaris or pemphigus foliaceus antigens. We describe a patient with an acantholytic bullous dermatosis and lung cancer with intercellular IgG and IgA antibodies that differed in specificity from those of pemphigus vulgaris and pemphigus foliaceus and reacted with bovine desmocollins I and II and recombinant desmocollin protein.

摘要

有一些寻常型天疱疮的特殊病例,其抗体与寻常型天疱疮或落叶型天疱疮抗原均无反应。我们描述了一名患有棘层松解性大疱性皮肤病和肺癌的患者,其细胞间IgG和IgA抗体的特异性不同于寻常型天疱疮和落叶型天疱疮,且与牛桥粒芯蛋白I和II以及重组桥粒芯蛋白发生反应。

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