Hallett J W, Bower T C, Cherry K J, Gloviczki P, Joyce J W, Pairolero P C
Division of Vascular Surgery, Mayo Clinic Rochester, Minnesota 55905.
Mayo Clin Proc. 1994 Aug;69(8):763-8. doi: 10.1016/s0025-6196(12)61096-9.
To discuss the most important risk factors in patients who undergo surgical repair of an abdominal aortic aneurysm (AAA).
This update in vascular surgical repair highlights the criteria that identify high-risk patients, the useful preoperative tests, and the perioperative measures that can aid surgical recovery.
In elective repair of AAAs, high-risk patients are those with severe coronary or valvular heart disease, decompensated chronic obstructive pulmonary disease, severe cerebrovascular disease, chronic renal failure, hepatic cirrhosis with portal hypertension, and chronic hematologic disorders associated with bleeding dysfunction. Patients with unstable or severely symptomatic heart disease should undergo preoperative coronary angiography and ventriculography. Pharmacologic stress testing is recommended for patients with clinical markers of serious coronary artery disease and other medical or physical factors that prevent any type of standard exercise stress testing.
Our experience with high-risk patients supports conventional repair of AAAs. Our preference for the midline abdominal incision in high-risk patients is substantiated by an operative mortality rate of 5.7% in comparison with a reported 7% mortality rate for nonresective therapy. Approximately one in three high-risk patients will have a serious postoperative complication, the most common of which is a cardiac event. Most patients recover after a slightly prolonged hospital stay.
Despite an increased operative risk, patients with a stable medical condition and an AAA larger than 6 cm in diameter should be considered for elective repair. High-risk patients with smaller aneurysms (5 to 6 cm in diameter) should undergo efforts to stabilize or to improve their general medical condition before elective operation.
探讨接受腹主动脉瘤(AAA)手术修复患者的最重要风险因素。
本次血管外科修复的更新内容强调了识别高危患者的标准、有用的术前检查以及有助于手术恢复的围手术期措施。
在AAA的择期修复中,高危患者包括患有严重冠状动脉或瓣膜性心脏病、失代偿性慢性阻塞性肺疾病、严重脑血管疾病、慢性肾衰竭、伴有门静脉高压的肝硬化以及与出血功能障碍相关的慢性血液系统疾病的患者。患有不稳定或严重症状性心脏病的患者应在术前进行冠状动脉造影和心室造影。对于有严重冠状动脉疾病临床标志物以及存在其他医学或身体因素而无法进行任何类型标准运动负荷试验的患者,建议进行药物负荷试验。
我们对高危患者的经验支持AAA的传统修复方法。我们在高危患者中倾向于采用中线腹部切口,其手术死亡率为5.7%,相比之下,非切除治疗的报告死亡率为7%。大约三分之一的高危患者会出现严重的术后并发症,其中最常见的是心脏事件。大多数患者在住院时间稍有延长后康复。
尽管手术风险增加,但对于病情稳定且AAA直径大于6 cm的患者,应考虑进行择期修复。直径较小(5至6 cm)的高危动脉瘤患者在择期手术前应努力稳定或改善其总体病情。