Köller H, Stoll G, Sitzer M, Burk M, Schöttler B, Freund H J
Department of Neurology, Heinrich-Heine-University, Düsseldorf, Germany.
Neurology. 1994 Jul;44(7):1238-40. doi: 10.1212/wnl.44.7.1238.
Protein C and protein S deficiencies increase the risk of venous thrombosis and pulmonary embolism, but their role in arterial thrombosis or embolism is controversial. We describe cerebral ischemia in two young women in a family with inherited deficiencies of both proteins C and S and provide evidence that a combined deficiency of proteins C and S may be a high risk factor for ischemic stroke in young adults.
蛋白C和蛋白S缺乏会增加静脉血栓形成和肺栓塞的风险，但其在动脉血栓形成或栓塞中的作用存在争议。我们描述了一个家族中两名患有蛋白C和蛋白S遗传性缺乏的年轻女性发生脑缺血的情况，并提供证据表明蛋白C和蛋白S的联合缺乏可能是年轻成年人缺血性中风的高风险因素。
