Kyriacou D N, Arcinue E L, Peek C, Kraus J F
Olive View/UCLA Medical Center, Department of Emergency Medicine, Sylmar 91342.
Pediatrics. 1994 Aug;94(2 Pt 1):137-42.
To determine the effect of immediate resuscitative efforts on the neurological outcome of children with submersion injury.
A case-control study was designed to determine if immediate resuscitation by rescuers or bystanders reduces the frequency of severe neurological damage or death in children with a documented submersion event. Logistic regression was used calculate an adjusted odds ratio.
The study group consisted of 166 children, aged zero to 14 years, having a submersion event during May 1984 through August 1992, and admitted through various emergency departments to Huntington Memorial Hospital in Pasadena, California.
All study subjects had an observed and documented episode of apnea at the time of submersion. Outcomes were evaluated on the basis of neurological impairment or death. Exposure was verified from historical accounts of postsubmersion events provided by family, friends, and/or paramedical personnel. The study factors included age and gender, duration of submersion, hypothermia, presence of apnea, resuscitative efforts, and clinical outcome. Children with a good outcome were 4.75 (adjusted odds ratio (OR)) times more likely to have a history of immediate resuscitation than children with poor outcome (95% confidence interval: 3.44 < OR < 6.06, P = .0001). Various types of resuscitative efforts and potential confounding factors were also evaluated. CPR and mouth-to-mouth resuscitation were the most effective types for the prevention of death or severe anoxic encephalopathy.
Immediate resuscitation before the arrival of paramedical personnel is associated with a significantly better neurological outcome in children with submersion injury.
确定即刻复苏措施对溺水儿童神经学转归的影响。
采用病例对照研究,以确定救援人员或旁观者进行即刻复苏是否能降低有记录的溺水事件患儿发生严重神经损伤或死亡的频率。使用逻辑回归计算调整后的优势比。
研究组由166名年龄在0至14岁之间的儿童组成,他们在1984年5月至1992年8月期间发生了溺水事件,并通过不同的急诊科入住加利福尼亚州帕萨迪纳市的亨廷顿纪念医院。
所有研究对象在溺水时均有观察到并记录在案的呼吸暂停发作。根据神经功能损害或死亡情况评估转归。通过家人、朋友和/或医护人员提供的溺水后事件的历史记录核实暴露情况。研究因素包括年龄、性别、溺水持续时间、体温过低、呼吸暂停情况、复苏措施及临床转归。转归良好的儿童接受即刻复苏的病史是转归不良儿童的4.75倍(调整后的优势比)(95%置信区间:3.44 <优势比< 6.06,P = .0001)。还评估了各种类型的复苏措施及潜在的混杂因素。心肺复苏和口对口复苏是预防死亡或严重缺氧性脑病最有效的类型。
在医护人员到达之前进行即刻复苏与溺水儿童显著更好的神经学转归相关。