Matsubara S
First Department of Surgery, Tohoku University, School of Medicine, Sendai, Japan.
Artif Organs. 1994 May;18(5):363-6. doi: 10.1111/j.1525-1594.1994.tb02217.x.
The combination of plasma exchange and continuous hemofiltration was applied to patients with acute liver failure, and its clinically advantageous effects were evaluated. This procedure was found to be a powerful approach in decreasing patient morbidity; however, the effect was temporary and the patients finally died. Efforts to eliminate the hepatitis virus, which is the main etiology of hepatic necrosis in Japan, are urgent to salvage patients with fulminant liver failure.
将血浆置换和连续性血液滤过联合应用于急性肝衰竭患者，并评估其临床优势效果。发现该方法在降低患者发病率方面是一种有效的途径；然而，效果是暂时的，患者最终死亡。在日本，消除作为肝坏死主要病因的肝炎病毒对于抢救暴发性肝衰竭患者的工作迫在眉睫。
