Lotter L P, Genigeorgis C A
Appl Microbiol. 1975 Feb;29(2):152-8. doi: 10.1128/am.29.2.152-158.1975.
Eight coagulase-negative, enterotoxigenic strains of cocci and one weakly coagulase-positive strain isolated from a number of different sources, including cases of food poisoning incidents, were evaluated for their relationship to Staphylococcus aureus on the basis of deoxyribonucleic acid (DNA) buoyant density and physiological studies. One strain of cocci produced enterotoxins A and C, two strains produced types B and C, four strains produced only type C, and one strain only type D. The enterotoxin produced by one strain of cocci was serologically untypable. None of the test organisms produced detectable amounts of enterotoxin in broth cultures. The test strains of cocci exhibited the following profile: all produced catalase; all grew anaerobically and fermented glucse; five were sensitive to lysostaphin; the percentage of guanine plus cytosine content of their DNA varied from 32.7 to 37.6; five produced acid from mannitol both aerobically and anaerobically; two formed delta-hemolysin; five produced phosphatase and acetoin; and all produced heat-stable nuclease. None of the organisms exhibited typical characteristics of S. aureus, S. epidermidis, or S. saprophyticus. On the basis of the present data and data reported elsewhere, these organisms should be considered as variants or mutants of S. aureus.
从包括食物中毒事件病例在内的多种不同来源分离出8株凝固酶阴性、产肠毒素的球菌菌株和1株弱凝固酶阳性菌株，基于脱氧核糖核酸（DNA）浮力密度和生理学研究评估了它们与金黄色葡萄球菌的关系。1株球菌产生肠毒素A和C，2株产生B型和C型，4株仅产生C型，1株仅产生D型。1株球菌产生的肠毒素在血清学上无法分型。在肉汤培养物中，受试生物均未产生可检测量的肠毒素。球菌受试菌株表现出以下特征：均产生过氧化氢酶；均能厌氧生长并发酵葡萄糖；5株对溶葡萄球菌素敏感；其DNA中鸟嘌呤加胞嘧啶的含量百分比在32.7%至37.6%之间；5株在需氧和厌氧条件下均能从甘露醇产酸；2株形成δ溶血素；5株产生磷酸酶和3-羟基丁酮；且均产生热稳定核酸酶。这些生物均未表现出金黄色葡萄球菌、表皮葡萄球菌或腐生葡萄球菌的典型特征。基于目前的数据和其他地方报道的数据，这些生物应被视为金黄色葡萄球菌的变体或突变体。
