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蛋白质-能量营养不良时的补钾、血清免疫反应性胰岛素浓度及葡萄糖耐量

Potassium supplementation, serum immunoreactive insulin concentrations and glucose tolerance in protein-energy malnutrition.

作者信息

Mann M D, Becker D J, Pimstone B L, Hansen J D

出版信息

Br J Nutr. 1975 Jan;33(1):55-61. doi: 10.1079/bjn19750008.

DOI:10.1079/bjn19750008
PMID:803838
Abstract

The serum immunoreactive insulin (IRI) concentrations, and glucose dissappearance rate-constants after intravenous glucose administration were measured on admission and during recovery in children suffering from protein-energy malnutrition (PEM). 2. A high potassium intake resulted in a considerable increase in the serum IRI levels early in the treatment period. There was a definite relationship between potassium depletion and many measurements of insulin secretion. 3. The results are consistent with the hypothesis that impaired insulin release in children suffering from PEM is partly the result of potassium depletion.

摘要
  1. 对患有蛋白质 - 能量营养不良(PEM)的儿童入院时及恢复期间测定了静脉注射葡萄糖后的血清免疫反应性胰岛素(IRI)浓度和葡萄糖消失速率常数。2. 在治疗初期,高钾摄入导致血清IRI水平显著升高。钾缺乏与许多胰岛素分泌测量值之间存在明确关系。3. 这些结果与以下假设一致,即患有PEM的儿童胰岛素释放受损部分是钾缺乏的结果。

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Potassium supplementation, serum immunoreactive insulin concentrations and glucose tolerance in protein-energy malnutrition.蛋白质-能量营养不良时的补钾、血清免疫反应性胰岛素浓度及葡萄糖耐量
Br J Nutr. 1975 Jan;33(1):55-61. doi: 10.1079/bjn19750008.
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Potassium depletion and impaired insulin release in protein-energy malnutrition.蛋白质 - 能量营养不良中的钾缺乏与胰岛素释放受损。
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Early insulin release and its response to potassium supplementation in protein-calorie malnutrition.蛋白质-热量营养不良时的早期胰岛素释放及其对补钾的反应。
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引用本文的文献

1
Hormonal changes in protein energy malnutrition.蛋白质能量营养不良中的激素变化。
Indian J Pediatr. 1988 Jul-Aug;55(4):465-9. doi: 10.1007/BF02868424.
2
Early insulin release and its response to potassium supplementation in protein-calorie malnutrition.蛋白质-热量营养不良时的早期胰岛素释放及其对补钾的反应。
Diabetologia. 1975 Jun;11(3):237-9. doi: 10.1007/BF00422328.