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[口腔黏膜表皮样癌的筛查与诊断。关于细胞学涂片和活检各自的作用,如今能得出哪些结论?]

[Screening and diagnosis of epidermoid carcinoma of the oral mucosa. What conclusions are possible today concerning the respective roles of cytologic smear and biopsy?].

作者信息

Vaillant J M

机构信息

Clinique de chirurgie maxillo-faciale et stomatologie, Groupe Hospitalier Pitié-Salpêtrière, C.H.U Pitié-Salpêtrière, Université Pierre et Marie Curie, Paris.

出版信息

Bull Acad Natl Med. 1994 Feb;178(2):233-43; discussion 243-7.

PMID:8039005
Abstract

Oral malignancies are a major problem in France where the consumption of alcoholic drinks is a traditional habit, often associated with heavy smoking. Contrary to other malignancies, at least in France mass screening has never been used to detect oral carcinoma. Preventive steps are very difficult to implement due to different economic reasons but mass screening in patients with records of heavy drinking/smoking, and/or pre-epitheliomatous lesions is an easy method after a short training of doctors in different specialties and cyto-pathologists. The mass screening is based upon the exfoliative character of the oral carcinomas which enables very easy and risk-free cytological smears and their classification in four grades. The reliability is more than 96%. However, Biopsy preserves its major importance for an accurate diagnosis but is most properly executed in cancer departments. This could bring oral cancer patients in adequate centers at a very early stage of the disease, and improve both prognosis and sequellae.

摘要

在法国,口腔恶性肿瘤是一个重大问题,该国饮酒是一种传统习惯,且常与大量吸烟相关。与其他恶性肿瘤不同,至少在法国,从未采用大规模筛查来检测口腔癌。由于各种经济原因,预防措施很难实施,但对有大量饮酒/吸烟记录和/或上皮瘤样病变的患者进行大规模筛查,在对不同专科医生和细胞病理学家进行短期培训后,是一种简便的方法。大规模筛查基于口腔癌的脱落特性,这使得非常容易且无风险地进行细胞学涂片,并将其分为四个等级。可靠性超过96%。然而,活检对于准确诊断仍然至关重要,但最适合在癌症科室进行。这可以使口腔癌患者在疾病的极早期被送到合适的中心,从而改善预后和后遗症。

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Bull Acad Natl Med. 1994 Feb;178(2):233-43; discussion 243-7.
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