果蝇核糖体S6激酶II编码序列。
The Drosophila melanogaster ribosomal S6 kinase II-encoding sequence.
作者信息
Wassarman D A, Solomon N M, Rubin G M
机构信息
Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California at Berkeley 94720-3200.
出版信息
Gene. 1994 Jul 8;144(2):309-10. doi: 10.1016/0378-1119(94)90396-4.
A cDNA encoding the Drosophila melanogaster p90 ribosomal S6 kinase II (RSK) was isolated from an eye-antennal imaginal disc library and sequenced. The conceptually translated protein is 60-63% identical to vertebrate RSK homologs and contains a perfectly conserved mitogen-activated protein kinase phosphorylation site. The gene was mapped to the base of the X chromosome in division 20 by in situ hybridization to polytene chromosomes.
从果蝇眼触角成虫盘文库中分离出编码黑腹果蝇p90核糖体S6激酶II（RSK）的cDNA并进行测序。经概念性翻译的蛋白质与脊椎动物RSK同源物有60 - 63%的同一性，且包含一个完全保守的丝裂原活化蛋白激酶磷酸化位点。通过对多线染色体进行原位杂交，该基因被定位到第20区X染色体的基部。
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