黑腹果蝇核糖体蛋白S4同源物编码基因的序列与表达

Sequence and expression of a gene encoding a ribosomal protein S4 homolog from Drosophila melanogaster.

作者信息

Yokokura T, Tei H, Yamamoto D

机构信息

Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan.

出版信息

Gene. 1993 Oct 15;132(2):251-4. doi: 10.1016/0378-1119(93)90203-f.

DOI:10.1016/0378-1119(93)90203-f

PMID:8224871

Abstract

We describe a Drosophila melanogaster cDNA clone encoding an amino acid (aa) sequence 75% identical to human ribosomal protein S4 (RPS4). The D. melanogaster RPS4 has 260 aa, if the NH2-terminal methionine is removed after translation of the mRNA. The mRNA for the protein is about 1 kb in length and is detected throughout the developmental stages tested (i.e., embryo, larva, pupa and adult). The cDNA clone hybridizes to two sites on the X chromosome, 1B1-2 and 3A3-6.

摘要

我们描述了一个黑腹果蝇cDNA克隆，其编码的氨基酸（aa）序列与人类核糖体蛋白S4（RPS4）有75%的同一性。如果在mRNA翻译后去除氨基末端的甲硫氨酸，黑腹果蝇RPS4有260个氨基酸。该蛋白的mRNA长度约为1 kb，在所有测试的发育阶段（即胚胎、幼虫、蛹和成虫）均能检测到。该cDNA克隆与X染色体上的两个位点杂交，即1B1-2和3A3-6。