Suzuki Y, Yonekura H, Watanabe T, Unno M, Moriizumi S, Miyashita H, Okamoto H
Department of Biochemistry, Tohoku University School of Medicine, Miyagi, Japan.
Gene. 1994 Jul 8;144(2):315-6. doi: 10.1016/0378-1119(94)90399-9.
We have isolated a rat cDNA and a novel gene, Reg (regeneration-promoting gene). The cDNA encodes a 174-amino-acid (aa) RegIII protein with a 25-aa signal peptide. The RegIII gene spans 2.7 kb and consists of six exons and five introns. RegIII was expressed in regenerating pancreatic islets, but not in normal islets.
我们分离出了一个大鼠cDNA和一个新基因Reg（促进再生基因）。该cDNA编码一种含25个氨基酸信号肽的174个氨基酸的RegIII蛋白。RegIII基因跨度为2.7 kb，由6个外显子和5个内含子组成。RegIII在再生的胰岛中表达，但在正常胰岛中不表达。
