Gideon P, Ståhlberg F, Thomsen C, Gjerris F, Sørensen P S, Henriksen O
Danish Research Center of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen, Denmark.
Neuroradiology. 1994 Apr;36(3):210-5. doi: 10.1007/BF00588133.
An interleaved velocity-sensitised fast low-angle shot pulse sequence was used to study cerebrospinal fluid (CSF) flow in the cerebral aqueduct, and supratentorial CSF production in 9 patients with normal pressure hydrocephalus (NPH) and 9 healthy volunteers. The peak aqueduct CSF flow, both caudal and rostral, was significantly increased in patients with NPH. No significant difference in the supratentorial CSF production rate was found between patients (mean 0.60 +/- 0.59 ml/min) and healthy volunteers (mean 0.68 +/- 0.31 ml/min). Our method may be useful for investigation and monitoring of patients with NPH before and after ventriculoperitoneal shunt operations.
采用交错式速度敏感快速低角度激发脉冲序列，对9例正常压力脑积水（NPH）患者和9名健康志愿者的中脑导水管脑脊液（CSF）流动及幕上CSF生成情况进行研究。NPH患者中脑导水管CSF向尾侧和头侧流动的峰值均显著增加。患者（平均0.60±0.59 ml/分钟）和健康志愿者（平均0.68±0.31 ml/分钟）的幕上CSF生成率无显著差异。我们的方法可能有助于在脑室腹腔分流手术前后对NPH患者进行检查和监测。
