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[自发缓解的纵隔-肺结节病的晚期复发]

[Late recurrences of spontaneously resolved mediastinal-pulmonary sarcoidosis].

作者信息

Tazi A, Desmazes-Dufeu N, Bozzolo B, Carvaillo D, Battesti J P

机构信息

Service de Pneumologie, Hôpital Avicenne, Bobigny.

出版信息

Rev Mal Respir. 1994;11(3):285-8.

PMID:8041992
Abstract

Five cases of recurrent thoracic sarcoidosis which happened 5.5 years on the average after spontaneous resolution of the disease are reported. Initially, these patients were characterized by the frequency of the presence of a Löfgren's syndrome and the absence of extrathoracic sarcoid localizations. Recurrence of sarcoidosis was potentially severe essentially because of extrathoracic localization which needed oral corticosteroid treatment in 2 patients. Because recurrence of sarcoidosis is rarely observed, the diagnosis should be, in the absence of erythema nodosum, confirmed histologically in order to exclude a lymphoma or one of the various etiologies of diffuse interstitial lung disease. A sustained and regular surveillance of sarcoid patients after spontaneous resolution, particularly those with a Löfgren's syndrome, is suggested.

摘要

报告了5例复发性胸段结节病,这些病例平均在疾病自然缓解5.5年后发生。最初,这些患者的特点是频繁出现 Löfgren 综合征且无胸外结节病定位。结节病复发可能较为严重,主要是因为胸外定位,2例患者需要口服皮质类固醇治疗。由于结节病复发很少见,在无结节性红斑的情况下,诊断应通过组织学确认,以排除淋巴瘤或弥漫性间质性肺病的各种病因。建议对结节病患者在自然缓解后进行持续、定期的监测,尤其是那些患有 Löfgren 综合征的患者。

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