Weström L V
Institute of Obstetrics and Gynecology, University of Lund, University Hospital, Sweden.
Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S32-7.
In both men and women, STD-associated genital infections may cause permanent damage to the reproductive tract resulting in sub- or infertility. In men, the wide zone between sterility and normal fertility makes it difficult to demarcate the precise role of infection on post-infection fecundity, but it seems less important than in women. The reproductive events were studied in a cohort of 1,309 pregnancy-seeking women, < or = 35 years of age, after laparoscopically verified acute salpingitis, and 451 women with normal laparoscopy. Tubal factor infertility (TFI) was diagnosed in 12.1% of the patients and 0.9% of the controls, and the first pregnancy was ectopic in 7.8% and 1.3%, respectively. Of independent importance for infertility, ectopic pregnancy, and time between PID and first intrauterine pregnancy were number of infections, severity of the infections, contraception at the index laparoscopy, age, and delayed treatment. STD-associated in-subfertility is acquired and, hence, preventable.
在男性和女性中，与性传播疾病相关的生殖器感染都可能对生殖道造成永久性损害，从而导致生育力低下或不育。在男性中，不育和正常生育能力之间的范围很广，因此很难界定感染对感染后生育能力的确切作用，但似乎不如在女性中那么重要。对一组1309名年龄小于或等于35岁、经腹腔镜检查确诊为急性输卵管炎的妊娠女性和451名腹腔镜检查正常的女性的生殖事件进行了研究。12.1%的患者和0.9%的对照组被诊断为输卵管因素不孕症（TFI），首次妊娠异位的比例分别为7.8%和1.3%。对于不育、异位妊娠以及盆腔炎发作到首次宫内妊娠之间的时间具有独立重要性的因素包括感染次数、感染严重程度、初次腹腔镜检查时的避孕措施、年龄以及治疗延迟。与性传播疾病相关的生育力低下是后天获得的，因此是可以预防的。
