Karlov V A
Zh Nevrol Psikhiatr Im S S Korsakova. 1993;93(1):33-6.
A study was made of the effect of the antiepileptic drug depakin (convulex). Depakin was combined with antiepileptic drugs used by the patients. As a rule, the dose of the latter drugs was reduced. Out of 108 patients, depakin was discontinued in 14 because of side effects. Out of the remaining 94 patients, excellent and positive results were obtained in 1/3 of the cases. The maximum effect was attained in myoclonic epilepsy of adolescent and juvenile age and in photogenic epilepsy, whereas the minimum effect was reached in infantile spasms and Lennox-Gastaut syndrome. The results appeared better in patients with a disease onset at an age of 6 to 16 years. The results become worse with increase of the disease standing.
对抗癫痫药物德巴金（丙戊酰胺）的效果进行了一项研究。德巴金与患者使用的其他抗癫痫药物联合使用。通常，后一种药物的剂量会减少。在108名患者中，有14名因副作用而停用德巴金。在其余94名患者中，三分之一的病例取得了优异和积极的效果。在青少年肌阵挛性癫痫和光诱发性癫痫中达到了最大效果，而在婴儿痉挛症和伦诺克斯-加斯东综合征中效果最小。在6至16岁发病的患者中结果似乎更好。随着病程的延长，结果会变差。
