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[从流行病学角度研究脑胶质瘤与伴发的脑病]

[Brain glioma and the concomitant encephalopathy studied from the epidemiological aspect].

作者信息

Savchenko A Iu, Zakharova N S, Lapchik S M

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1993;93(1):70-4.

PMID:8042370
Abstract

Based on an analysis of 1,255 cases of brain gliomas operated during 30 years, a relative constancy of the disease incidence together with enhancement of its expressivity was discovered. As compared with the typical forms, the growth of malignant tumors of the astrocytic type was revealed, as was a great number of patients with neoplasms spreading to several lobes of the brain as well as of patients manifesting the neurological symptomatology since the first days of life. As compared to the tumor disease incidence in the population, noticeable predominance of oncological diseases was established in the families of patients with brain gliomas. Some meteorological phenomena correlate with certain epidemiological parameters in brain gliomas. 75% of patients with gliomas were found to have diseases that possess an immunodepressive action. It is not excluded that these diseases may be among the causes of encephalopathy progression in the postoperative period.

摘要

基于对30年间1255例脑胶质瘤手术病例的分析,发现该疾病发病率相对恒定,但其表现度有所增强。与典型形式相比,发现星形细胞型恶性肿瘤生长,以及大量肿瘤扩散至脑多个叶的患者,还有自出生第一天就表现出神经症状的患者。与人群中的肿瘤疾病发病率相比,脑胶质瘤患者家庭中肿瘤疾病明显占优势。一些气象现象与脑胶质瘤的某些流行病学参数相关。发现75%的胶质瘤患者患有具有免疫抑制作用的疾病。不排除这些疾病可能是术后脑病进展的原因之一。

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