Mjöberg B
Department of Orthopedics, Uppsala University Hospital, Sweden.
Acta Orthop Scand. 1994 Jun;65(3):361-71. doi: 10.3109/17453679408995473.
The observation of perioprosthetic granulomas containing wear debris around apparently well-fixed as well as around loose-fitting prosthetic components has led to the development of the hypothesis of wear-induced loosening. However, the hypothesis of wear-induced loosening can neither explain the rapid early prosthetic migration detected by roentgen stereophotogrammetry nor the epidemiology of clinical failure without supplementary ad hoc-assumptions. By contrast, apart from explaining the rapid early prosthetic migration detected by roentgen stereophotogrammetry, the theory of early loosening can explain the development of wear granulomas as well as to a great extent the epidemiology of clinical failure.
在表面固定良好以及松动的假体组件周围均观察到含有磨损碎屑的假体周围肉芽肿，这促使了磨损导致松动假说的形成。然而，磨损导致松动的假说，若没有补充的特别假设，既无法解释通过X线立体摄影测量法检测到的早期假体快速移位，也无法解释临床失败的流行病学情况。相比之下，早期松动理论除了解释通过X线立体摄影测量法检测到的早期假体快速移位外，还能解释磨损肉芽肿的形成，并且在很大程度上能解释临床失败的流行病学情况。
