Teng R J, Chen B W, Ho M M
Department of Pediatrics, National Taiwan University Hospital, Taipei. R.O.C.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1994 May-Jun;35(3):225-8.
A female newborn was delivered prematurely at gestational age of 26 weeks with birth weight of 1,000 grams. Her initial white blood cell count was 68,900/mm3, which increased to 207,000/mm3 on the fifth day of life with a remarkable shift-to-left pattern. The most immature myeloid series in the peripheral blood smear was promyelocyte; and the promyelocyte, myelocyte and meta-myelocyte accounted for 38% of the peripheral white blood cells. Neither hepatosplenomegaly nor skin rash was noted, but the platelet count dropped to 86,000/mm3 transiently on Day 8. Cytogenetic study for the bone marrow aspiration revealed normal results. The leukemoid reaction recovered within three weeks without specific treatment. Antenatal usage of steroid to promote lung maturation was considered to be one possible cause of the transient leukemoid reaction.
一名女婴在孕26周时早产，出生体重1000克。她出生时白细胞计数为68900/mm³，出生后第5天升至207000/mm³，呈现明显的核左移现象。外周血涂片最不成熟的髓系细胞是早幼粒细胞；早幼粒细胞、中幼粒细胞和晚幼粒细胞占外周白细胞的38%。未发现肝脾肿大和皮疹，但第8天血小板计数短暂降至86000/mm³。骨髓穿刺的细胞遗传学研究结果正常。类白血病反应在三周内未经特殊治疗自行恢复。产前使用类固醇促进肺成熟被认为是短暂性类白血病反应的一个可能原因。
