Freeman J A, Armstrong I R
Department of Anaesthetics, Western General Hospital, Edinburgh.
Anaesthesia. 1994 Jul;49(7):579-82. doi: 10.1111/j.1365-2044.1994.tb14223.x.
Pulmonary function tests were performed in 22 patients undergoing laparoscopic cholecystectomy. Measurements were made before, 24 h after, and 6 weeks after operation (12 patients). At 24 h postoperatively there were significant decreases in forced expiratory volume in 1 s, vital capacity, functional residual capacity and total lung capacity to 75% (p < 0.001), 73% (p < 0.001), 92% (p = 0.002) and 83% (p < 0.001) of pre-operative values respectively. Inspiratory and expiratory mouth pressures decreased to 66% (p < 0.001) and 63% (p < 0.001) of the pre-operative pressures respectively. There was a reduction in PaO2 (p < 0.01) and an increase in alveolar-arterial gradient (p < 0.001) but no change in PaCO2 at 24 h. The pulmonary function tests measured in the patients who returned after 6 weeks had returned to pre-operative values.
对22例行腹腔镜胆囊切除术的患者进行了肺功能测试。在手术前、术后24小时以及术后6周（12例患者）进行测量。术后24小时，第1秒用力呼气量、肺活量、功能残气量和肺总量显著下降，分别降至术前值的75%（p<0.001）、73%（p<0.001）、92%（p = 0.002）和83%（p<0.001）。吸气和呼气口压分别降至术前压力的66%（p<0.001）和63%（p<0.001）。术后24小时，动脉血氧分压降低（p<0.01），肺泡-动脉氧分压差增加（p<0.001），但动脉血二氧化碳分压无变化。6周后复查的患者肺功能测试结果已恢复至术前值。
