Tocchi A, Costa G, Lepre L, Liotta G, Mazzoni G
Cattedra di IV Patologia Chirurgica, Università degli Studi La Sapienza, Roma.
G Chir. 1997 Mar;18(3):87-90.
A prospective analysis of 58 patients undergoing laparoscopic cholecystectomy was undertaken to assess pulmonary function changes related to the surgical procedure. Pulmonary function tests were performed preoperatively, as well as 24 hrs., and 48 hrs. after operation. Additionally blood gas analysis was assessed 1 hr. and 6 hrs. after the procedure. At 24 hrs. from operation significant decreases in forced vital capacity, forced expiratory volume in 1", and Tidal volume to 72% (p < 0.001), 70% (p < 0.001), and 92% (p < 0.001) of preoperative values respectively were registered. There was a reduction in PaO2 (p < 0.001) and an increase in PaCO2 (p < 0.05) at 24 hrs. An increase in PaCO2 was also observed 1 hr. (p < 0.001) and 6 hrs. (p < 0.05) postoperatively. Blood gas analysis revealed pH value slightly lower than normal at 1 hr. from operation (p < 0.01). The pulmonary function tests returned to preoperative values at 48 hours.
对58例行腹腔镜胆囊切除术的患者进行前瞻性分析，以评估与手术相关的肺功能变化。术前、术后24小时和48小时进行肺功能测试。此外，术后1小时和6小时进行血气分析。术后24小时，用力肺活量、第1秒用力呼气量和潮气量分别显著下降至术前值的72%（p<0.001）、70%（p<0.001）和92%（p<0.001）。术后24小时，动脉血氧分压降低（p<0.001），动脉血二氧化碳分压升高（p<0.05）。术后1小时（p<0.001）和6小时（p<0.05）也观察到动脉血二氧化碳分压升高。血气分析显示术后1小时pH值略低于正常（p<0.01）。肺功能测试在48小时恢复到术前值。
