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1,2,3-Triazole[4,5-d]pyridazines--II. New derivatives tested on adenosine receptors.

作者信息

Biagi G, Giorgi I, Livi O, Scartoni V, Martini C, Tacchi P, Merlino S, Pasero M

机构信息

Istituto di Chimica Farmaceutica e Tossicologica, Università di Pisa.

出版信息

Farmaco. 1994 Mar;49(3):175-81.

PMID:8043168
Abstract

This paper reports the synthesis and biological evaluation towards A1 and A2 adenosine receptors of new 1,2,3-triazole[4,5-d]pyridazines bearing lipophilic substituents in the 1 position. Some 1-benzyl-4-substituted amino derivatives were prepared and the cyclohexylamino-, anilino- and p-toluidino- derivatives showed an interesting moderately selective activity on the A1 receptor.

摘要

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