Harrison P, Chipping P, Fothergill G A
Department of Haematology, North Staffordshire Hospital, Stoke-on-Trent.
Br J Haematol. 1994 Mar;86(3):681-2. doi: 10.1111/j.1365-2141.1994.tb04811.x.
The development of acute leukaemia in pregnancy is a rare event, with an estimated incidence of 0.9-1.2 cases per 100,000 per year and with the majority of cases occurring in the second and third trimesters. We report a case of acute promyelocytic leukaemia (APL) developing during the second trimester of pregnancy which was successfully treated with all-trans retinoic acid (ATRA) resulting in a complete morphological remission.
妊娠期急性白血病的发生是一种罕见事件，估计每年每10万人中有0.9 - 1.2例，且大多数病例发生在妊娠中期和晚期。我们报告一例在妊娠中期发生的急性早幼粒细胞白血病（APL），该病例通过全反式维甲酸（ATRA）成功治疗，实现了完全形态学缓解。
