Bissett D, Lamont D W, Nwabineli N J, Brodie M M, Symonds R P
Beatson Oncology Centre, Western Infirmary, Glasgow, UK.
Br J Obstet Gynaecol. 1994 Jul;101(7):615-20. doi: 10.1111/j.1471-0528.1994.tb13653.x.
To examine the results of different treatments for Stage IA and IB carcinoma of the cervix in patients treated in the West of Scotland between 1980 and 1987.
A retrospective review of case records.
The Beatson Oncology Centre, Western Infirmary and Belvidere Hospital, Glasgow, and the departments of gynaecology of hospitals in the west of Scotland.
One hundred and five patients with Stage IA and 420 patients with Stage IB carcinoma of the cervix.
A variety of treatments were used for women with Stage IA disease, with an overall actuarial five year survival of 100%. The overall actuarial five year survival for women with Stage IB disease was 79.5%. Patients with Stage IB disease treated by radical hysterectomy (n = 123) or radical radiotherapy (n = 229) had similar five year survival rates (86.3% and 79.5%, respectively), whereas patients treated initially by nonradical surgery (n = 68) had a significantly worse five year survival (68.1%; P = 0.008).
These results emphasize the need for adequate and appropriate surgery and the centralisation of treatment for early cervical cancer.
研究1980年至1987年间在苏格兰西部接受治疗的IA期和IB期宫颈癌患者不同治疗方法的结果。
病例记录回顾性研究。
格拉斯哥的Beatson肿瘤中心、西部医院和贝尔维德雷医院，以及苏格兰西部各医院的妇科。
105例IA期宫颈癌患者和420例IB期宫颈癌患者。
IA期疾病的女性患者采用了多种治疗方法，总体精算五年生存率为100%。IB期疾病女性患者的总体精算五年生存率为79.5%。接受根治性子宫切除术（n = 123）或根治性放疗（n = 229）的IB期疾病患者的五年生存率相似（分别为86.3%和79.5%），而最初接受非根治性手术治疗的患者（n = 68）的五年生存率明显较差（68.1%；P = 0.008）。
这些结果强调了早期宫颈癌进行充分且适当手术以及集中治疗的必要性。
