Mutant of Dictyostelium discoideum defective in cell contact regulation of enzyme expression.
作者信息
Brackenbury R, Sussman M
出版信息
Cell. 1975 Apr;4(4):347-51. doi: 10.1016/0092-8674(75)90155-5.
PMID:804355
Abstract
Previous work has shown that aggregation and disaggregation of cells during development of D. discoldeum significantly affects the expression of certain developmentally regulated enzymes. We have examined this cell contact regulation in a previously isolated mutant, Fr-17, and found that during the course of its developmental sequence it becomes specifically defective in this function.
摘要
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引用本文的文献
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Specific cell-cell contacts are essential for induction of gene expression during differentiation of Dictyostelium discoideum.在粘菌盘基网柄菌的分化过程中，特定的细胞-细胞接触对于基因表达的诱导是必不可少的。
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