Müller-Leisse C, Bussmann A, Mayer O, Genth E, Günther R W
Klinik für Radiologische Diagnostik, Landesversicherungsanstalt Rheinprovinz.
Rofo. 1994 Jul;161(1):12-8. doi: 10.1055/s-2008-1032485.
To determine pulmonary features of collagenous vascular diseases as assessed by high resolution computed tomography (HRCT) we performed a prospective study of 73 consecutive patients, 44 with rheumatoid arthritis (ra), 11 with progressive systemic sclerosis (pss), 8 with systemic lupus erythematosus (sle), 5 with sjögren's syndrome, 3 with dermato-/polymyositis and 2 with mixed connective-tissue disease. Pathological lung changes were demonstrated in 70% of patients with ra, 91% with pss, 63% with sle and 60% with the rest. HRCT features included: intralobular thickening (48%) with a predominance in posterior lower and middle lung areas, pleural thickening (48%) with a predominance in upper lung areas, prominent interlobular septa (37%), subpleural lines (33%), parenchymal bands (33%) with a predominance in lower and anterior lung areas, honeycombing (33%), ground glass pattern (29%) with a predominance in upper and middle, micronodules (18%) with a predominance in upper lung areas and bronchiectasis (14%). HRCT is an important means for the assessment of lung changes associated with collagenous vascular diseases and a definite diagnosis is possible in most cases.
为了通过高分辨率计算机断层扫描（HRCT）确定胶原血管疾病的肺部特征，我们对73例连续患者进行了一项前瞻性研究，其中44例患有类风湿性关节炎（RA），11例患有进行性系统性硬化症（PSS），8例患有系统性红斑狼疮（SLE），5例患有干燥综合征，3例患有皮肌炎/多肌炎，2例患有混合性结缔组织病。70%的RA患者、91%的PSS患者、63%的SLE患者以及60%的其他疾病患者出现了病理性肺部改变。HRCT特征包括：小叶内增厚（48%），以下肺后部和中部区域为主；胸膜增厚（48%），以上肺区域为主；小叶间隔增厚（37%）；胸膜下线（33%）；实质带（33%），以下肺前部区域为主；蜂窝状改变（33%）；磨玻璃影（29%），以上肺和中肺为主；微小结节（18%），以上肺区域为主；支气管扩张（14%）。HRCT是评估与胶原血管疾病相关的肺部改变的重要手段，大多数情况下可以做出明确诊断。
