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[胶原病的肺部高分辨率CT]

[HRCT of the lung in collagenoses].

作者信息

Diederich S, Roos N, Schmitz-Linneweber B, Gaubitz M, Peters P E

机构信息

Institut für Klinische Radiologie, Westfälische Wilhelms-Universität Münster.

出版信息

Radiologe. 1996 Jul;36(7):567-78. doi: 10.1007/s001170050112.

Abstract

Collagen vascular diseases, representing systemic soft tissue disorders, may cause a broad spectrum of pathologic changes of the respiratory tract. The type and extent of manifestations can vary considerably among individuals and entities. This survey describes the chest radiographic and, in particular, high-resolution computed tomographic (HRCT) findings of individual lesions of the respiratory tract. It includes fibrosing alveolitis (alveolitis, interstitial pneumonia, pulmonary fibrosis) and bronchial (bronchitis/bronchiolitis, bronchiectasis), pleural and vascular manifestations, as well as lymphadenopathy and abnormalities related to therapy. We present typical patterns of changes in progressive systemic sclerosis (PSS, scleroderma), systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD, Sharp syndrome), Sjögren syndrome, overlap syndrome and rheumatoid arthritis (RA). Furthermore, we describe findings which are specific for individual entities such as esophageal involvement in PSS, acute pneumonitis and pulmonary hemorrhage in SLE, lymphoproliferative disease in Sjögren syndrome and necrobiotic nodules in RA.

摘要

胶原血管疾病是全身性软组织疾病,可导致呼吸道广泛的病理变化。其表现的类型和程度在个体和病种之间差异很大。本综述描述了呼吸道单个病变的胸部X线表现,尤其是高分辨率计算机断层扫描(HRCT)表现。它包括纤维化肺泡炎(肺泡炎、间质性肺炎、肺纤维化)、支气管(支气管炎/细支气管炎、支气管扩张)、胸膜和血管表现,以及淋巴结病和与治疗相关的异常。我们展示了进行性系统性硬化症(PSS,硬皮病)、系统性红斑狼疮(SLE)、混合性结缔组织病(MCTD,夏普综合征)、干燥综合征、重叠综合征和类风湿关节炎(RA)的典型变化模式。此外,我们还描述了个别病种的特异性表现,如PSS中的食管受累、SLE中的急性肺炎和肺出血、干燥综合征中的淋巴增殖性疾病以及RA中的渐进性坏死结节。

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