Mudraia I S, Kirpatovskiĭ V I, Martov A G, Kudriavtsev Iu V, Makarova T I
Biull Eksp Biol Med. 1993 Feb;115(2):144-7.
S-stents were introduced to the upper urinary tracts of experimental dogs on a period from 1 week to 11 months. It was found mild ureter dilation, the increased ureter pressure, refluxes along the upper urinary tract, the lowered flow resistance during perfusion and diuretic loads. Isolated ureter wall fragments demonstrated the diminished contractility in vitro, and the mode of their contractile force adrenergic regulation was modified. The reduced ureter pressure during large flows after indwelling S-stents to the ureters may be the factor that facilitated the renal and ureter stones removing but the decreased contractility and ureter refluxes emphasized that the period of stent implantation to the upper urinary tracts must be pathogenetically and clinically evident.
将S型支架植入实验犬的上尿路，时间从1周持续到11个月。发现有轻度输尿管扩张、输尿管压力升高、上尿路出现反流、灌注和利尿负荷期间的血流阻力降低。分离出的输尿管壁碎片在体外显示收缩力减弱，其收缩力的肾上腺素能调节模式发生改变。将S型支架留置在输尿管后，大流量时输尿管压力降低可能是促进肾和输尿管结石排出的因素，但收缩力降低和输尿管反流表明，在上尿路植入支架的时间在发病机制和临床上都必须明确。
