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[实验性糖尿病中急性胰腺炎兔血清因子在胰岛B细胞刺激再生中的种属特异性]

[Species specificity of serum factors in rabbits with acute pancreatitis in stimulated regeneration of pancreatic islet B-cells in experimental diabetes].

作者信息

Zharkov V P, Iarygin V N, Dolzhikov A A

出版信息

Biull Eksp Biol Med. 1993 May;115(5):536-7.

PMID:8043848
Abstract

The experiment has shown that the serum of rabbits with acute pancreatitis produces proliferative effect on pancreatic islets' B-cells in rats with the acute form of experimental diabetes. The stimulation of miotic activity of B-cells, processes of acino-insular transformation, compensation of the insular function in rats with alloxan diabetes proved to be lower than in rabbits under the same experimental conditions. This testities to relative species specificity of factors in the serum of rabbits with pancreatic gland trauma.

摘要

实验表明，急性胰腺炎兔的血清对实验性糖尿病急性发作大鼠的胰岛B细胞产生增殖作用。在相同实验条件下，四氧嘧啶糖尿病大鼠的B细胞有丝分裂活性刺激、腺泡-胰岛转化过程以及胰岛功能代偿均低于兔。这证明了胰腺创伤兔血清中各因素具有相对的种属特异性。

相似文献

1
[Species specificity of serum factors in rabbits with acute pancreatitis in stimulated regeneration of pancreatic islet B-cells in experimental diabetes].[实验性糖尿病中急性胰腺炎兔血清因子在胰岛B细胞刺激再生中的种属特异性]
Biull Eksp Biol Med. 1993 May;115(5):536-7.
2
[Serum factors in rabbits with acute pancreatitis as stimulators of regeneration of pancreatic islet B-cells in experimental diabetes].[急性胰腺炎家兔血清因子作为实验性糖尿病中胰岛B细胞再生刺激物的研究]
Biull Eksp Biol Med. 1993 May;115(5):525-7.
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Alloxan sensitivity of rats at various intervals following ligation of the pancreatic ducts.胰腺导管结扎后不同时间间隔大鼠对四氧嘧啶的敏感性。
Acta Soc Med Ups. 1971;76(1-2):77-86.
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[Structure of Langerhans islands and secretory vesicles of the pancreas in rats with alloxan diabetes of 6-week duration].[六周持续性四氧嘧啶糖尿病大鼠的胰岛结构及胰腺分泌囊泡]
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Functional and morphological studies of islet beta-cell regeneration in endogenous and exogenous diabetes.内源性和外源性糖尿病中胰岛β细胞再生的功能和形态学研究
Acta Pathol Microbiol Scand A. 1970;78(4):496.
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[The state of the pancreatic islets, fetal weight and the glucose tolerance test among the progeny of male rats with alloxan diabetes].
Biull Eksp Biol Med. 1974 Sep;78(9):34-6.
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Hepatic regeneration promotes engraftment of intraportally transplanted islet cells.肝脏再生促进经门静脉移植胰岛细胞的植入。
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In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.急性胰腺炎中胰蛋白酶对明胶酶B/基质金属蛋白酶-9的体内激活是链脲佐菌素诱导糖尿病的一个促成因素。
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