[实验性糖尿病中急性胰腺炎兔血清因子在胰岛B细胞刺激再生中的种属特异性]
[Species specificity of serum factors in rabbits with acute pancreatitis in stimulated regeneration of pancreatic islet B-cells in experimental diabetes].
作者信息
Zharkov V P, Iarygin V N, Dolzhikov A A
出版信息
Biull Eksp Biol Med. 1993 May;115(5):536-7.
PMID:8043848
Abstract
The experiment has shown that the serum of rabbits with acute pancreatitis produces proliferative effect on pancreatic islets' B-cells in rats with the acute form of experimental diabetes. The stimulation of miotic activity of B-cells, processes of acino-insular transformation, compensation of the insular function in rats with alloxan diabetes proved to be lower than in rabbits under the same experimental conditions. This testities to relative species specificity of factors in the serum of rabbits with pancreatic gland trauma.
摘要
实验表明，急性胰腺炎兔的血清对实验性糖尿病急性发作大鼠的胰岛B细胞产生增殖作用。在相同实验条件下，四氧嘧啶糖尿病大鼠的B细胞有丝分裂活性刺激、腺泡-胰岛转化过程以及胰岛功能代偿均低于兔。这证明了胰腺创伤兔血清中各因素具有相对的种属特异性。
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