Kohl P K, Henze I, Kamionek I, Krahl D, Petzoldt D
Universitäts-Hautklinik, Ruprecht-Karls-Universität Heidelberg.
Gesundheitswesen. 1994 May;56(5):276-9.
Auxotype/serovar (A/S) classification enables precise characterisation of Neisseria gonorrhoeae. In the present study we evaluated whether sex and sexual preference of the patient influence the auxotype/serovar class of the infecting gonococcal strain. In male patients prototrophic/IB-3 was the most frequently isolated A/S class. By contrast, in female patients the A/S class (P)AH(U)/IA-1/2 was significantly (p < 0.005) more frequently isolated than in male patients. Analysis of our data according to sexual preference of the patients showed that in heterosexual patients the two mentioned A/S classes were leading, whereas in homo- and bisexual patients A/S classes prototrophic/IB-2 (p < 0.0001) and Pro/IB-2/16 (p < 0.0001) were isolated significantly more often. Our data are a strong indication that the host environment is also responsible for the selection of N. gonorrhoeae strains with certain typing characteristics.
菌型/血清型（A/S）分类有助于精确鉴定淋病奈瑟菌。在本研究中，我们评估了患者的性别和性取向是否会影响感染的淋病菌株的菌型/血清型类别。在男性患者中，原养型/IB-3是最常分离出的A/S类别。相比之下，在女性患者中，A/S类别（P）AH（U）/IA-1/2的分离频率显著高于男性患者（p < 0.005）。根据患者的性取向对我们的数据进行分析表明，在异性恋患者中，上述两种A/S类别占主导地位，而在同性恋和双性恋患者中，原养型/IB-2（p < 0.0001）和Pro/IB-2/16（p < 0.0001）的分离频率明显更高。我们的数据有力地表明，宿主环境也参与了具有特定分型特征淋病奈瑟菌菌株的选择。
