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70岁以上患者的经皮引流肾造瘘术。关于74例患者的98例肾造瘘术

[Percutaneous drainage nephrostomy in patients over 70 years of age. Apropos of 98 nephrostomies in 74 patients].

作者信息

Fournier G, Delavierre D, Le Coat R, Philippe P, Mangin P

机构信息

Service d'Urologie, Hôpital Morvan, CHU de Brest.

出版信息

Prog Urol. 1994 Jun;4(3):362-70.

PMID:8044179
Abstract

From 1985 to 1992, 98 ultrasound-guided percutaneous drainage nephrostomies were performed in 74 patients with a mean age of 77 years (range: 70-88 years). The diversion was indicated because of upper urinary tract obstruction (87% of cases), urinary fistula (4%) or secondary displacement of the first PCN (9%). The initial disease was benign in 29 patients (42.5%, including 48% of renal and ureteric stones), malignant in 39 cases (53%, including 79% of pelvic cancers) and not specified in 6 cases (4.5%). PCN was performed successfully in 93% of patients and allowed improvement in renal failure and/or treatment of the initial infectious syndrome in the majority of cases. The following complications were observed: secondary displacement of the drain (13 cases), infection (3 cases), renal subcapsular haematoma (1 case). The outcome of the patients was directly related to the initial disease: 28 of the 29 patients diverted for a benign disease were still alive and the PCN drain was able to be removed in 96% of cases after curative treatment; 95% of the patients diverted for cancer had died within 13 months after PCN. Patients with previously untreated prostatic cancer had the best prognosis, as androgen suppression allowed removal of the PCN without any additional procedure, in some cases. Drainage of the upper urinary tract by percutaneous nephrostomy under local anaesthesia has a limited morbidity and a low failure rate and therefore appears to be a technique of choice, particularly in elderly patients.

摘要

1985年至1992年期间,对74例平均年龄77岁(范围:70 - 88岁)的患者进行了98次超声引导下经皮引流肾造瘘术。进行引流的指征是上尿路梗阻(87%的病例)、尿瘘(4%)或首次经皮肾穿刺造瘘术(PCN)的继发移位(9%)。初始疾病为良性的有29例(42.5%,包括48%的肾和输尿管结石),恶性的有39例(53%,包括79%的盆腔癌),6例(4.5%)未明确。93%的患者PCN操作成功,多数情况下肾功能衰竭得到改善和/或初始感染综合征得到治疗。观察到以下并发症:引流管继发移位(13例)、感染(3例)、肾包膜下血肿(1例)。患者的预后与初始疾病直接相关:因良性疾病接受引流的29例患者中有28例仍存活,96%的病例在根治性治疗后能够拔除PCN引流管;因癌症接受引流的患者中95%在PCN术后13个月内死亡。既往未治疗的前列腺癌患者预后最佳,因为在某些情况下,雄激素抑制可使PCN引流管无需额外操作即可拔除。局部麻醉下经皮肾穿刺造瘘对上尿路进行引流,发病率有限且失败率低,因此似乎是一种首选技术,尤其适用于老年患者。

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