Jacobsen M, Baelum J, Bonde J P
Department of Occupational Medicine, University Hospital of Arhus, Denmark.
Occup Environ Med. 1994 Jun;51(6):429-30. doi: 10.1136/oem.51.6.429.
Long term exposure to organic solvents is usually not considered as a possible cause of chronic epileptic seizures. A case that shows a remarkable coincidence between exposure to organic solvents and occurrence of epileptic seizures is reported. The man was a 58 year old sign writer with lifelong exposure to a mixture of organic solvents (mainly cyclohexanone, white spirit, and isopropanol). Epileptic seizures of temporal type were occurring in relation to solvent exposure. The seizures disappeared shortly after stopping exposure but returned just after a short term re-exposure to cyclohexanone. The case history suggests that exposure to organic solvents may elicit or maintain epileptic seizures despite medical treatment.
长期接触有机溶剂通常不被认为是慢性癫痫发作的可能原因。本文报告了一例有机溶剂暴露与癫痫发作之间存在显著巧合的病例。该男子为一名58岁的招牌书写工，终生接触有机溶剂混合物（主要是环己酮、白酒精和异丙醇）。与溶剂暴露相关的颞叶型癫痫发作时有发生。停止接触后癫痫发作很快消失，但在短期再次接触环己酮后又复发。该病例史表明，尽管进行了药物治疗，但接触有机溶剂可能引发或维持癫痫发作。
