McColl J H, Holmes A P, Ford I
Department of Statistics, University of Glasgow, UK.
Stat Methods Med Res. 1994;3(1):63-86. doi: 10.1177/096228029400300105.
We review statistical methods being applied in four key areas connected with PET and SPECT neuroimaging: (i) image reconstruction (briefly); (ii) tracer-kinetic, or compartmental, modelling; (iii) inference from region-of-interest data; (iv) inference at the pixel or voxel level. Under the last heading, we pay particular attention to the analysis of data from serial scans. We conclude by identifying some topics for future statistical research.
我们回顾了正电子发射断层扫描（PET）和单光子发射计算机断层扫描（SPECT）神经成像相关的四个关键领域中所应用的统计方法：（i）图像重建（简要介绍）；（ii）示踪剂动力学或房室模型；（iii）基于感兴趣区域数据的推断；（iv）像素或体素水平的推断。在最后一个主题下，我们特别关注来自系列扫描数据的分析。我们通过确定一些未来统计研究的主题来结束本文。
