Calderone R A
Dept of Microbiology, Georgetown University School of Medicine, Washington, DC 20007-2197.
Trends Microbiol. 1993 May;1(2):55-8. doi: 10.1016/0966-842x(93)90033-n.
The cell surface of Candida albicans is a complex mosaic of polysaccharide and protein, of which mannoproteins constitute the major antigens and host cell recognition molecules. One group of mannoproteins is known as 'adhesins' and has properties similar to lectins and integrins. The adhesins recognize either host cell fucosyl glycosides or peptides containing the amino acid sequence arginine-glycine-aspartic acid (RGD peptides).
白色念珠菌的细胞表面是多糖和蛋白质的复杂镶嵌体,其中甘露糖蛋白构成主要抗原和宿主细胞识别分子。一类甘露糖蛋白被称为“黏附素”,具有与凝集素和整合素相似的特性。黏附素可识别宿主细胞岩藻糖基糖苷或含有精氨酸 - 甘氨酸 - 天冬氨酸氨基酸序列的肽(RGD肽)。