Thind P, Lose G, Colstrup H, Andersson K E
Department of Urology, Rigshospitalet, University of Copenhagen, Denmark.
Br J Urol. 1994 Jul;74(1):86-92. doi: 10.1111/j.1464-410x.1994.tb16552.x.
To examine the influence of autonomic receptor stimulation and blockade (noradrenaline, prazosin, terbutaline, propranolol, carbachol and atropine), and of pudendal nerve blockade on urethral stress relaxation.
Forty healthy women were evaluated. The stress relaxation parameter was defined as the relative rate of pressure decrease during a fixed period of time following a rapid dilatation of the urethra. The dilatation was performed by water-infusion into a small rubber cylinder placed in the urethra.
The drugs did not affect stress relaxation significantly, whereas the pudendal blockade produced a significant change along the length of the urethra characterized by a faster pressure decay following dilatation.
In women, stress relaxation in the urethra relies significantly on the pudendal nerve-innervated striated muscles.
研究自主神经受体刺激和阻断（去甲肾上腺素、哌唑嗪、特布他林、普萘洛尔、卡巴胆碱和阿托品）以及阴部神经阻断对尿道压力性松弛的影响。
对40名健康女性进行评估。压力性松弛参数定义为尿道快速扩张后固定时间段内压力下降的相对速率。扩张通过向置于尿道内的小橡胶囊注水来进行。
药物对压力性松弛无显著影响，而阴部神经阻断使尿道全长产生显著变化，其特征为扩张后压力衰减更快。
在女性中，尿道压力性松弛显著依赖于阴部神经支配的横纹肌。
