Nduka C C, Monson J R, Menzies-Gow N, Darzi A
Academic Surgical Unit, St Mary's Hospital Medical School, London, UK.
Br J Surg. 1994 May;81(5):648-52. doi: 10.1002/bjs.1800810506.
Only 18 cases of recurrence at the sites of cannula insertion after laparoscopy have been reported in the literature, ten of them in the past year. The period between laparoscopic surgery and presentation of wound metastasis varies widely, from 7 days to 10 months; the lesions are typically hard, craggy and painful. The most likely mechanism is direct implantation of viable exfoliated tumour cells but three aspects specific to laparoscopy may also be important. First, there may be increased exfoliation of tumour cells following manipulation by laparoscopic instruments of an unsuspected malignancy. Second, there may be repeated close contact between tumour-laden instruments and the port. Third, the passage of resected tissue through a small incision may coat the wound with potentially malignant cells.
文献中仅报道了18例腹腔镜检查后套管插入部位复发的病例,其中10例是在过去一年中出现的。腹腔镜手术与伤口转移出现之间的时间间隔差异很大,从7天到10个月不等;病变通常质地坚硬、凹凸不平且伴有疼痛。最可能的机制是存活的脱落肿瘤细胞直接植入,但腹腔镜检查特有的三个方面可能也很重要。首先,腹腔镜器械对未被怀疑的恶性肿瘤进行操作后,肿瘤细胞的脱落可能会增加。其次,载有肿瘤的器械与端口之间可能会反复密切接触。第三,切除的组织通过小切口时可能会使伤口覆盖上潜在的恶性细胞。