Wallesch C W, Hundsalz A
Department of Neurology, Albert-Ludwigs-University, Freiburg, Germany.
Brain Lang. 1994 May;46(4):592-606. doi: 10.1006/brln.1994.1032.
Thirteen patients suffering from transient acute confusional states (ACS) and 11 patients with probable Alzheimer's disease (AD) who were comparable for age and Mini-Mental State score were investigated with a naming and a comprehension task. The latter included both words that were previously included in the naming task and unfamiliar items. With five patients of each group, the assessment was repeated 1 to 3 days later. The number of misnamings was comparable for both groups. An effect of word frequency upon naming success was found only with the AD group. Unrelated misnamings were significantly more frequent in the ACS group. Closer analysis suggested that part of the unrelated misnamings in the ACS patients were caused by visual misperceptions. Behavioral strategies aiming at the target were more frequently exhibited by Ad patients. Perseverations, especially of the intrusion type, were characteristic for ACS patients and only occasionally found with AD. There was an item consistency over time with naming failure in the AD, but not in the ACS group. Cross-modal performance consistency seemed greater in the ACS than in the AD group.
对13名患有短暂急性意识模糊状态（ACS）的患者和11名年龄及简易精神状态评分相当的疑似阿尔茨海默病（AD）患者进行了命名和理解任务研究。后者包括先前已纳入命名任务的单词以及不熟悉的项目。每组各有5名患者，在1至3天后重复进行评估。两组的错误命名数量相当。仅在AD组中发现词频对命名成功率有影响。ACS组中无关错误命名明显更为频繁。进一步分析表明，ACS患者中部分无关错误命名是由视觉误认引起的。AD患者更频繁地表现出针对目标的行为策略。持续行为，尤其是侵入型持续行为，是ACS患者的特征，在AD患者中仅偶尔出现。AD组存在随时间推移在命名失败方面的项目一致性，但ACS组不存在。跨模态表现一致性在ACS组似乎比在AD组更大。
