肉芽肿性皮肤松弛症
Granulomatous slack skin.
作者信息
LeBoit P E
机构信息
Dermatopathology Section, University of California, San Francisco.
出版信息
Dermatol Clin. 1994 Apr;12(2):375-89.
Granulomatous slack skin is a form of cutaneous lymphoma with an indolent but relentless course. It is characterized by circumscribed areas of pendulous lax skin that contain clonal infiltrates of helper T-cells, which infiltrate the epidermis in a manner similar to that of mycosis fungoides and attract a granulomatous component that mediates massive dermal elastolysis. The evolution of Hodgkin's disease occurs in some cases. There is no known curative treatment, but surgery, radiation therapy, systemic corticosteroids, and chemotherapy have slowed the progression of some lesions.
肉芽肿性皮肤松弛症是一种皮肤淋巴瘤，病程进展缓慢但持续存在。其特征为局限性的皮肤下垂松弛区域，其中含有辅助性T细胞的克隆性浸润，这些细胞以类似于蕈样肉芽肿的方式浸润表皮，并吸引介导大量真皮弹性组织溶解的肉芽肿成分。在某些情况下会发生霍奇金病的演变。目前尚无已知的治愈性治疗方法，但手术、放射治疗、全身性皮质类固醇和化疗已减缓了一些病变的进展。
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