Guthrie J A, Saifuddin A, Simpkins K C, deDombal F T
General Infirmary at Leeds.
Clin Radiol. 1994 Jun;49(6):375-8. doi: 10.1016/s0009-9260(05)81820-3.
The incidence on double contrast barium enema (DCBE) of carcinomas and polyps > 1 cm in size was compared in 92 patients with iron deficiency anaemia and a group of randomly obtained non-anaemic controls. In the anaemic group there were eight carcinomas and four polyps, and in the control group two carcinomas and no polyps. The incidence of neoplasms in the anaemic group (13.0%) was significantly greater than in the control group (1.6%). The incidence of neoplasms in iron-deficient males was 19% compared with 9% in females. The presence of bowel symptoms or weight loss were not found to be significant. This study confirms the value of DCBE in investigating patients with unexplained iron deficiency anaemia even in the absence of bowel symptoms.
对92例缺铁性贫血患者和一组随机选取的非贫血对照者进行了比较，观察双对比钡灌肠（DCBE）检查中大小>1 cm的癌和息肉的发生率。贫血组有8例癌和4例息肉，对照组有2例癌且无息肉。贫血组肿瘤发生率（13.0%）显著高于对照组（1.6%）。缺铁男性的肿瘤发生率为19%，女性为9%。未发现肠道症状或体重减轻有显著意义。本研究证实了DCBE在调查不明原因缺铁性贫血患者中的价值，即使在没有肠道症状的情况下也是如此。
