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[小原发性肝癌的合理手术治疗方法及术后复发的预防]

[Rational surgical approaches to the treatment of small primary liver cancer, and the prevention of postoperative recurrence].

作者信息

Ma Z M, Feng Y Z, Zhou X R

机构信息

First Affiliated Hospital, Zhejiang Medical University, Hangzhou.

出版信息

Zhonghua Wai Ke Za Zhi. 1994 Jan;32(1):31-4.

PMID:8045198
Abstract

From Sep. 1985 to Dec. 1990, surgical treatment was performed in 27 patients with small primary liver cancer (SPLC, < or = 5cm in diameter). Of them, segmentectomy was done in 23 cases and radical local resection in 4 cases with recurrence rate of 66.77% (18/27). Non recurrent lesions were located in the incisal margin. In this group re-resection rate was 55.6% (10/18). (1) Early detection and treatment of recurrent lesions remain a mainstay of prolonging survival. (2) Serum Alpha-fetoprotein (AFP), ultrasonography and X-ray chest film were basic follow-up methods for subclinical recurrence of SPLC. For re-operation cases, digital subtract angiography (DSA) are useful in identifying subclinical lesions. (3) For recurrent liver cancer local hepatectomy was a reasonable approach. (4) For SPLC, radical segmentectomy or radical local resection with a safe margin of 1 to 2cm was the authors' choice.

摘要

1985年9月至1990年12月,对27例原发性小肝癌(直径≤5cm)患者实施了手术治疗。其中,23例行肝段切除术,4例行根治性局部切除术,复发率为66.77%(18/27)。未复发的病灶位于手术切缘。该组再次手术率为55.6%(10/18)。(1)复发病灶的早期发现与治疗仍是延长生存期的关键。(2)血清甲胎蛋白(AFP)、超声检查及胸部X线片是原发性小肝癌亚临床复发的基本随访方法。对于再次手术的病例,数字减影血管造影(DSA)有助于识别亚临床病灶。(3)对于复发性肝癌,局部肝切除术是一种合理的方法。(4)对于原发性小肝癌,作者选择行根治性肝段切除术或切缘安全距离为1至2cm的根治性局部切除术。

相似文献

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[Rational surgical approaches to the treatment of small primary liver cancer, and the prevention of postoperative recurrence].[小原发性肝癌的合理手术治疗方法及术后复发的预防]
Zhonghua Wai Ke Za Zhi. 1994 Jan;32(1):31-4.
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[Recurrence and treatment of primary liver cancer after radical hepatectomy].根治性肝切除术后原发性肝癌的复发与治疗
Zhonghua Wai Ke Za Zhi. 1991 Feb;29(2):93-6, 141-2.
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[Surgical treatment of primary liver cancer].[原发性肝癌的外科治疗]
Zhonghua Wai Ke Za Zhi. 1996 Dec;34(12):707-10.
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Survival factors after resection of small hepatocellular carcinoma.小肝细胞癌切除术后的生存因素。
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Micrometastasis in surrounding liver and the minimal length of resection margin of primary liver cancer.原发性肝癌周围肝组织中的微转移及手术切缘的最小长度
World J Gastroenterol. 2007 Sep 7;13(33):4498-503. doi: 10.3748/wjg.v13.i33.4498.