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[正常状态及心功能不全各阶段人体心肌的收缩性与能量代谢]

[Contractility and energy metabolism in human myocardium in normal state and in various stages of cardiac insufficiency].

作者信息

Shevchuk V H, Frantsuzova S B, Horchakova N O, Plyska O I, Babak V V, Arshynnykova L L, Lazoryshynets V V, Iakymovych V V

出版信息

Fiziol Zh (1978). 1993 Sep-Dec;39(5-6):18-23.

PMID:8045312
Abstract

Contractile function and metabolism of byoptates of human myocardium were investigated in the control group and at early stages of heart failure development. Support of the myocardial contractile function at the early stage of the heart failure is provided by intensive use of macroergic phosphates and their insufficient resynthesis. At the late stages of myocardial failure deterioration of the heart muscle relaxation was observed as a result of disturbances in transport of high-ergic phosphates to the sites of their utilization.

摘要

在对照组以及心力衰竭发展的早期阶段,对人心肌活检组织的收缩功能和代谢进行了研究。在心力衰竭早期,心肌收缩功能的维持是通过大量利用高能磷酸酯且其再合成不足来实现的。在心肌衰竭的后期,由于高能磷酸酯向其利用部位的转运出现障碍,观察到心肌舒张功能恶化。

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