Golubeva L Iu, Dzhaparidze L M
Vopr Med Khim. 1986 Nov-Dec;32(6):121-2.
Vitamin E deficient diet of rats developed impairments in energy metabolism of myocardium, involving a decrease in content of creatine phosphate and in the activity of creatine phosphokinase by 20-35%. Concentration of adenine nucleotides was not altered in myocardium and the content of glycogen was only slightly changed. The impairments in activity of creatine phosphokinase and in the content of creatine phosphate might be among the factors responsible for deterioration of the heart muscle contractile functions in avitaminosis E.
给大鼠喂食缺乏维生素E的饮食会导致心肌能量代谢受损，包括磷酸肌酸含量降低以及磷酸肌酸激酶活性降低20%-35%。心肌中腺嘌呤核苷酸的浓度没有改变，糖原含量仅略有变化。磷酸肌酸激酶活性和磷酸肌酸含量的受损可能是维生素E缺乏症中心肌收缩功能恶化的因素之一。
