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[将牙周膜成纤维细胞直接移植到牙齿颈部——正畸治疗潜力扩展中的一步?]

[The direct transplantation of desmodont fibroblasts onto the necks of the teeth--a step in the expansion of the treatment potentials in orthodontics?].

作者信息

Schendel K U, Lohr A, Komposch G

机构信息

Poliklinik für Kieferorthopädie, Universität Heidelberg.

出版信息

Fortschr Kieferorthop. 1994 Jun;55(3):126-31. doi: 10.1007/BF02341485.

Abstract

The loss of periodontal support, especially of the periodontal ligament, presents the orthodontist with a constraining factor precisely in the treatment of patients who have reached adult and senior citizen age. Given this situation it was decided to take small biopsies of periodontal ligament cells, grow them, amplify them in vitro, and then with the help of different types of membranes, some of which consisted of resorbable materials, which served as cell carriers, transplant them onto tooth roots. The work reported here constitutes a starting point for research aimed at actively and directly re-populating tooth roots with periodontal ligament fibroblasts and thus, by improving the overall periodontal condition, widen the spectrum of treatment possibilities open to the orthodontist.

摘要

牙周支持组织的丧失,尤其是牙周韧带的丧失,给正畸医生在治疗成年和老年患者时带来了一个制约因素。鉴于这种情况,决定取牙周韧带细胞的小活检组织,进行培养,在体外扩增,然后借助不同类型的膜(其中一些由可吸收材料组成,用作细胞载体),将它们移植到牙根上。本文报道的工作构成了一项研究的起点,该研究旨在通过牙周韧带成纤维细胞积极、直接地重新填充牙根,从而改善整体牙周状况,拓宽正畸医生的治疗可能性范围。

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