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爱尔兰患者的软组织和内脏肉瘤。都柏林软组织肿瘤小组所获数据的中期分析。

Soft tissue and visceral sarcomas in Irish patients. Interim analysis of data obtained by the Dublin Soft Tissue Tumour Panel.

作者信息

Gaffney E F, Dervan P A, McCabe M M, Sheahan K, Kay E W, Leader M, Doyle J, Daly P A, Fennelly J J, Carney D N

机构信息

Department of Histopathology, St. James's Hospital, Dublin, Ireland.

出版信息

Ir J Med Sci. 1994 May;163(5):240-5. doi: 10.1007/BF02943260.

Abstract

The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in the prospective series were treated by 93 different surgical and medical specialists. Tumours presented in all anatomic sites and ranged in size from 0.2 to 60 cm. Leiomyosarcoma was the commonest tumour type. Eighty-nine tumours were inoperable at clinical presentation. There was a consensus panel diagnosis in over 90%, non-neoplastic reactive lesions and primitive round cell tumours being the most difficult cases diagnostically. Management, including onward referral for chemotherapy or radiation therapy, was inconsistent. The 2-year survival figures were: 43% (1989-91) and 37% (1980-88). These findings should provide a basis for the evaluation of coherent treatment strategies for Irish sarcoma patients.

摘要

都柏林软组织肉瘤小组于1989年成立,旨在实现对软组织和内脏肉瘤诊断与管理的统一方法。这份中期报告展示了265例接受前瞻性评估患者以及另一组126例回顾性患者的数据。前瞻性队列中的患者由93位不同的外科和内科专家进行治疗。肿瘤出现在所有解剖部位,大小从0.2厘米至60厘米不等。平滑肌肉瘤是最常见的肿瘤类型。89例肿瘤在临床表现时无法手术切除。超过90%的病例有小组共识诊断,非肿瘤性反应性病变和原始圆形细胞瘤是诊断上最困难的病例。包括转介接受化疗或放疗在内的管理并不一致。两年生存率分别为:43%(1989 - 91年)和37%(1980 - 88年)。这些发现应为评估爱尔兰肉瘤患者的连贯治疗策略提供依据。

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