Weidner F, Gall H
MMW Munch Med Wochenschr. 1975 Jan 3;117(1):3-8.
Drug-induced allergic skin reactions of the eczema type may relatively frequently appear as allergic contact eczema or more rarely as "hematogenous contact eczema." In both types of eczema, a positive patch test to one or more allergens is essential for diagnosis. In 1971 and 1972, there were 85 patients with drug-induced eczema reactions (allergic reactions to the ointment bases and preservatives have not been taken into consideration). In 80 cases, topical applications were the contact allergens. The frequent contact allergies to benzocaine and Balsam of Peru seems significant. In 5 isolated cases we saw hematogenous contact eczema due to internal medication, e.g. with antibiotics.
药物性湿疹型皮肤过敏反应可能相对频繁地表现为过敏性接触性皮炎,或更罕见地表现为“血源性接触性皮炎”。在这两种类型的湿疹中,对一种或多种过敏原进行斑贴试验呈阳性对诊断至关重要。1971年和1972年,有85例药物性湿疹反应患者(未考虑对软膏基质和防腐剂的过敏反应)。在80例病例中,局部用药是接触性过敏原。对苯佐卡因和秘鲁香脂频繁的接触过敏似乎很显著。在5例孤立病例中,我们发现了因内服药物,如抗生素导致的血源性接触性皮炎。